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العنوان
CLINICAL VALUES OF SUPEROXIDE DISMUTASE
AND MALONDIALDEHYDE DETECTION IN CORD
BLOOD OF NEWBORNS WITH FETAL DISTRESS
المؤلف
MOSTAFA,SAFAA MOSTAFA AHMED
هيئة الاعداد
باحث / SAFAA MOSTAFA AHMED MOSTAFA
مشرف / Safaa Shafik Imam
مشرف / Nermine Hussein Sayed Amr
مشرف / Soheir Saad Korraa
الموضوع
Oxidative stress in perinatal asphyxia-
تاريخ النشر
2009
عدد الصفحات
123.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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Abstract

Perinatal asphyxia is a common cause of morbidity
and mortality in term newborns. In addition perinatal
hypoxic ischemic encephalopathy which still the major
cause of long term neurological sequalae in childhood
develops in one third of asphyxiated infants (Nagdyman
et al., 2001).
Numerous studies have suggested that free radicals
could have a key role in hypoxic ischemic brain damage
(Ogihera et al., 2003).
The aim of this study was; first to assess the value
of malondialdehyde (lipid peroxidation product) measured
in the umbilical cord blood as a marker of foetal asphyxia
and as a predictor for hypoxic ischemic encephalopathy,
and second was to assess the balance between oxidant
and antioxidant generating system in the face of foetal
asphyxia.
We prospectively studied 50 term newborns divided
into 25 patients (13 males, 12 females) had perinatal
asphyxia, and 25 ages matched controls (11 males, 14
females).