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Abstract Due to the spread of disease caused by microbial infections, the development of new antimicrobial materials became urgent matter. To avoid problems accompaired with the conventional antimicrobial agent, the antimicrobial polymers seems promising solution with new advantage over the conventional ones. The aim of the present study is to introduce, synthesize new antimicrobial polymers to overcome the disadvantages with the molecular weight analuges. This work in this the thesis is distributed into four chapters. Chapter I: Involves the chemical modification of Linear and branched poly (p-hydroxystyrene) by using chloroacetyl chloride to form active groups. The chloroacetylated derivatives were further modified with triethylamine and triphenylphosphine. The antimicrobial activities of the synthesized polymers were explored against various microorganisms. Chapter 2: Involves the modifications of the branched p l y (phydroxystyrene) (BPHS) with chloroacetyl chloride, then the chloroacetylated BPHS, was treated with ethylenediamine to introduce the mine functionality to the BPHS. The arninated polymer was then modified with various aldehydes and esters with expected antimicrobial activities. All the modified polymers in this chapter were tested against selected microorganisms. |