الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The diagnosis of BA, particularly distinguishing it from other causes of liver injury in the neonatal period, is challenging as there is a high decree of overlap m clinical, biochemical, imaging, and histological characteristics. It is of paramount importance to differentiate BA from other causes of NC early as the success of Kasai portoenterostomy is directly related to the age of the child. However, making a definite diagnosis before subjecting a child to lapEirotomy and peroperative cholangiogram is not an easy task. No single teat is 100% accurate.This prospective study included 7£ patients recruited over a period of two years (2009-20 U), from the Pediatric Hepatolo&y department, National Liver Institute, Minofiya University, and department of Pediatrics, faculty of medicine, Minofiya University. The studied infants were 53 infants with cholestasis and 25 non-hepatic infants. After confirming the final diagnosis, they were divided into three groups- The first group (Gr.I) including patients with BA (n - 27). Patients of Gr.I who underwent Kasai operation were 24 cases. They underwent follow up after Kasai operation (clinically, US color Doppler and laboratory). The second group (Gr.U) including patients with cholestasis due to other causes than BA (n - 26). The third &roup (Gr.U) was non-hepatic infants and nconates (n = 25)Our results showed that:1- Clinically: Clay stool was found in 92.6% of BA and in a considerable percent (42%) of non-BA. Clay stool had a high sensitivity (92,5%) and NPV (88,2%), but low specificity.