الفهرس 
ELECTROCARDIOGRAM ANDOnly 14 pages are availabe for public view
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Abstract
T
his study included 30 patients with acute ST segment elevation anterior myocardial infarction. They were 25 males (83.3%) and 5 females (16.7%). During the period from January 2009 to January 2010, they were classified according to QRS duration into 2 groups. Group I enrolled 18 patients with QRS duration <100ms. They were 17 males(94.4%) and 1 female(5.6%) Group II enrolled 12 patients with QRS duration >100ms. They were 8 males (66.7%) and 4 females (33.3%). All patients underwent 12 leads ECG on admission and after 24hrs, then mean QRS duration was calculated. All patients were received thrombolytic therapy and monitored for MACE (cardiovascular death, recurrent MI, heart failure, CVS).then the patients were assessed by echocardiographic study including 2D, M-mode, Doppler echocardiography for estimation of LVEDD, LVESD, EF% (by modified Simpson’s rule) The data of all patients were coded and fed to the computer for statistical analysis using computer program SPSS/PC version 15 (SPSS inc. Chicago, IL, USA).
Continuous variables were presented as mean and standard deviation. Categorical variables were presented as percentage.
Comparison between continuous variables were done using paired student’s t-test.
Comparison between categorical variables was done using chi-square test.
Pearson product moment correlation coefficient was done to find out the presence of significant correlation between QRS duration and the different parameters.
95% confidence interval was used with P < 0.05 as a significant level. There was no significant difference between the two groups regarding their mean age, prevalence of the different risk factors for coronary artery disease (P > 0.05).
There was significant difference between the two groups regarding the sex distribution and heart rate i.e. females had more prolonged QRS, the higher heart rate was associated also with more prolonged QRS duration (P < 0.05). Patients in group II (QRS >100msec.) had a significantly lower LV systolic function as assessed by EF.
MACE: 17 patients of group I had no MACE vs. 2 patients of group II. No cardiovascular death occurred in group I and the most common complication was recurrent MI. While in group II; cardiovascular death occurred in 3 patients (25%), recurrent MI in 1 patient (8.3%), heart failure in 4 patients (33.3%), CVS in 1 patient (8.3%) and resuscitated sudden death in 1 patient (8.3%). The incidence of MACE was significantly higher in patients of group II than that of group I (P < 0.001).