الفهرس | Only 14 pages are availabe for public view |
Abstract Hepatocellular carcinoma (HCC), the most common solid organ tumor worldwide, is responsible for 1 million deaths yearly. The majority of cases of HCC occur in areas where viral hepatitis is endemic (Yuman Fong et al., 2004). In patients with localized HCC, liver resection is currently one of the best therapeutic options that could offer a chance of long-term survival. However, most HCCs are associated with chronic liver disease and in particular liver cirrhosis. Liver resection in this setting is associated with a high risk of postoperative complications due to the poor functional reserve of the liver or impaired and delayed ability of the liver to regenerate (Roger Noun et al., 2003). LR offers a surgical death rate of less than 1.5%, a 5-year survival rate of approximately 50%, a 5-year recurrence rate of more than 60%, and a 5-year tumor-free survival rate of 28% when performed in specialized centers (Gian Luca Grazi et al., 2006) In the current study we tried to limit the possibility of confounding factors contributing to the results, by matching the demographic and clinical criteria of both groups as well as the tumor site, size and number of lesions so that they did not differ significantly. Thus, making sure that the reason for the change in liver function was only due to the influence of stem cell therapy . |