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العنوان
Assessment of regression of hepatic pathology following combined treatment of chronic hepatitis C (genotype 4) among responders and non-responders using transient elastography./
المؤلف
Ibrahim,Ahmed Mostafa Ahmed
هيئة الاعداد
باحث / أحمد مصطفى أحمد ابراهيم
مشرف / يحى محمد الشاذلى
مشرف / خالد زكريا القرموطى
مشرف / أحمد على مؤنس
مشرف / شريف منير محمد
مشرف / ريهام عزت الصواف
الموضوع
Assessment of regression of hepatic pathology following combined treatment of chronic hepatitis C (genotype 4,among responders ,and non-responders using transient elastography.
تاريخ النشر
2011
عدد الصفحات
163.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الباطني
تاريخ الإجازة
1/12/2011
مكان الإجازة
جامعة عين شمس - كلية الطب - قسم الباطنة
الفهرس
Only 14 pages are availabe for public view

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from 163

Abstract

The recent advent of non-invasive methods for assessment of liver fibrosis allows serial assessment in all patients with hepatitis C to determine their response to treatment.
Transient elastography measures tissue stiffness. It can measure liver sample size 100 times greater than a standard biopsy sample size, as liver biopsy size strongly affects the grading of chronic viral hepatitis.
The aim of the study was to assess regression of hepatic fibrosis following combined treatment of chronic hepatitis C (genotype 4) among responders and non-responders using transient elastography.
The study was carried out on 40 chronic HCV infected patients who received combined treatment. According to the sustained virological response patients were divided into two groups, 20 patients who achieved SVR and 20 patients who did not achieve SVR. Fibroscan was done before and after treatment for all patients.
The results of the current study revealed that there was a significant decrease in Fibroscan value and METAVIR score among responders and non-responders after receiving treatment compared to pre-treatment values which would signify regression of liver fibrosis in both groups.