الفهرس 
COPDOnly 14 pages are availabe for public view
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Abstract
C
hronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality and is characterized by chronic air flow limitation. Many people suffer from this disease for many years and die prematurely from it or its complications.
COPD produce significant extra pulmonary (systemic) manifestations including nutritional abnormalities, weight loss, skeletal muscle dysfunction, anemia.
Vitamin D is a fat soluble vitamin that is naturally present in very few foods, added to others and available as dietary supplement, it is biologically inert and must undergo two hydroxylation in the body for activation.
Patients with COPD were considered at high risk for vitamin D deficiency for variety of reasons such a lower food intake, reduced capacity of aging skin from vitamin D synthesis.
Aim of the work:
To study the serum level of 25-hydroxyvitamin D in stable chronic obstructive pulmonary disease patients.
Subjects and methods:
The present study was conducted on (80) subjects: (20) healthy male smokers, (60) stable male patients with chronic obstructive pulmonary disease with its different stages, diagnosis was on the basis of (Gold, 2009), they were coming the chest outpatient clinic of Ain Shams University Hospital.
All patients were subjected to history taking, careful general and local examination, chest X ray, post bronchodilator pulmonary function studies, Laboratory tests and estimation of serum 25(OH) D in serum by ELISA.