الفهرس 
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Abstract
Diabetic nephropathy (DN) is a common long-term complication of
diabetes. It starts by minor damage hyperfiltration, and progresses,
especially if untreated, to chronic kidney disease.
endothelial nitric oxide synthase (eNOS) plays an important role in
regulation of endothelial function and in the control of blood pressure.
The eNOS protein synthesizes nitric oxide constitutively via reaction
including the conversion of L-arginine to L-citrulline
a point mutation of guanine to thymine at nucleotide position G894T
in the endothelial nitric oxide synthase (eNOS) gene within exon 7, resulting
in a replacement of glutamic acid by aspartic acid at codon 298
(Glu298Asp),has been reported to be associated with Diabetic nephropathy
This work is organized to investigate the effect of G894T SNPs of
eNOS gene on the genetic predisposition for diabetic nephropathy among
Egyptian types1, 2 diabetes patients.