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Abstract Laser in situ keratomileusis (LASIK) is the most commonly performed procedure in refractive surgery and the first choice for the correction of refractive errors in the majority of patients. One of the most common complications is LASIK-associated dry eye, which is believed to be attributable to the transectionol large numbers of the afferent sensory nerve fibers in the cornea during the lamellar cut. This impacts the integrated lacrimal gland-ocular surface functional unit and promotes the development of LASIK-associated dry eye. Several preoperative (female gender, race, preexisting dry eye syndrome) as well as intraoperative (hinge-related, highly attempted corrections, and ablation depth) risk factors have been correlated with the development of dry eye after LASIK. Understanding these risk factors can assist the refractive surgeon in selecting effective strategies to optimize the ocular surface prior to surgery, which in turn can result in improved refractive outcomes. Many diagnostic methods including serological and histological techniques can be held to predict the post operative results of the operation which finally influence the patient satisfaction. The management of dry eye include preoperative screening examination and individualized treatment regimen devised to prepare whether the patient is a candidate for LASIK treatment of these conditions include topical preparations like artificial tears lid scrubs and topical cyclosporine A or the usage of tear retention techniques like punctal plugs and contact lens. Other biological tears substitute like autologous serum and salivar gland autotransplantation can be of a great usage. |