الفهرس | Only 14 pages are availabe for public view |
Abstract Alginate is a family of non-branched binary co-polymers of 1-4 glycosidically linked . D-mannuronic acid and a-L-gulurenic acid residues, the relative amount of the two uronic acid monomers and their sequential arrangement vary widely, depending on the alginate origin. The tensile properties and characteristics of alginate hydro-gels make it suitable for industrial applications, specifically, high Guluronic alginate content yielded stronger gel. The aim of study was to isolate some useful biopolymers from Egyptian brown algae and investigate their biotechnological applications. in bio-control, water treatment (heavy metal <removal) and antimicrobial activity, especially as wound dressing. Five brown algal species have been collected from the Egyptian Mediterranean Sea, at Abu Quir bay. Their alginate polymer content was isolated and completely characterized by phenol sulfuric method, IR and NMR techniques, in which Sargassum vulgare species gave the highest Guluronic acid content. The extracted alginates were successfully examined for inhibition of the Agrobacterium tumefaciens tumorigenic activity using potato discs anti- turnor bioassay, in which Padina pavonia sodium alginate with high content of mannuronic acid gave anti-tumor inhibition of 68%. Sargassum vulgare Mg-alginate gave a high capacity for heavy metal removal from water, comparing with other legends. Antimicrobial activities against Pseudomonas aeruginosa and Escherichia coli were evaluated to asses its possible application as wound dressing material, especially for diabetic ulcer patients. |