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Abstract 1. INTRODUCTION Brucellosis is an infectious and contagious disease caused’ by bacteria of the genus Brucella; it primarily affects cattle, sheep, goats, swine and dogs, anti is characterized by abortion or infertili y. I is also considered CIne of the most i portant ba terial anthropozoonotic diseases that affects uman and is cham terized by intermittent fever, chills, night sweating, headache, myalgia, arthralgia and a diversity of non-specific symptoms (Metcalfet aI.. 1994). Brucellosis remains a . erious zoonosis of bod public healtl and economic significance in many developing countries. World Health Organization (WHO) reported half million new cases worldwide each year but these numbers an: said to .be greatly underestimate the true incidence of human disease (WHO. 1997). Brucello is i caused by members of the genus Brucella which includes Brucella abortlls Brucello: melitensis, Brucella suis and Brucella cQnis. Brucella melitensis is considered the most virulent and pathogenic strain among different Brucella species for both animals and man (Elberg, 1986). It can be transmitted from infected animals to man either directly or indirectly, direct transmissiou occurs through contact with infected animals and their secretions so the disease is considered largely an occuperional disease affectspeople such as veterinarians, fanners, slaughterhouse workers and pathologists; while the indirect |