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Abstract Abstract This study was carried out to study the changes occurring on characteristic of ICU admitted COPD patients in acute exacerbation. For this purpose 100 patients ( 76 males and 24 females with a mean age of 64.68±6.87 years ) with acute exacerbation of COPD admitted at the ICU of Respiratory Department, Zagazig University Hospitals were included. They were classified according to management they received into 3 groups. Group I: They under conservative treatment only. They were 20 patients; 14 males and 6 females with a mean age of 62.4±6.62 years. Group II: They under NIV plus conservative treatment. They were 20 patients; 14 males and 6 females with a mean age of 65.33±6.8 years. Group III: They under invasive mechanical ventilation (IMV) plus conservative treatment. They were 60 patients; 48 males and 12 females with a mean age of 65±7.16 years. On admission to ICU the followings were carried out for all patients: - Full medical history from the patient (if possible) or his relatives. - Full clinical examination: (General & local). - Plain chest and heart X – ray. - Arterial blood gases analysis. |