الفهرس 
الملخص العربى
Development and structure of the pineal glandOnly 14 pages are availabe for public view
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Abstract
FINAL CONCLUSION AND SUMMARY
The pineal gland had become the subject of considerable
investilSa tion during the past decade in a trial to study the
f~ction of the pineal gland in different animal species.
from the literature, the biological activity of the
camel was least studied. This work was
d~e as a trial to investigate some chemical constituents
extract of camel and to stuuy’ the g13ca~o
extract in mature male fasting rabbits and
its effect on the 02consumption of tissue slices of albino
Pineal bodies were collected from mature camel from
slaughter house. The saL0les were collected ~edi-
after slaughter of the animals and were preserved iri
ice containers and transported to the laboratory where they
tept io deep”freeze for future use.
The pineal extract was prepared according to the method
of Milcu et al., (196)a). The average yield in this method
was 36.3 mg proteinic nitrogen/lOO ml pineal extract.
The reduction percent of 02consQ~ption after the
of melatonin was significantly lower (P~ 0.001) kidney slices when compared with that obtained after
e addition of the highest dose of the pineal extract.
significant changes in average reduction
rcent of 02conswnption of brain, liver, heart, intestine
slices after the addition of the melatonin with that obtained after the addition of dose of the pineal extract.
In all tissues th8 reduction percent in the 02consump¬tion produced by melatonin is more than that produced by serotonin, although the dose of melatonin was only about
These finding proved tbllt the inhibitory effect of
02consumption is due to mainly to presence of serotonin and melatonin and also the potency of melatonin is much more than serotonin.
Final Conclusi on:
from this work, it c an be concluded that the pineal. extract of camel possesses a biological activity which can
pared to the pineal extracts of other animal species. is a similarity in the chemical composition of the
et in the amino acids and indole derivative contents. of camel was shown to possess a effect in mature male rabbits, accompaned increase in the liver glycogen content. The increase glycogen content was inversly correlated with in blood glucose level in treated groups. This glycaemic effect may be attributed to insulin like
1vity of the pineal extract, potentiation of insulin
the 6vialbilty of insulin due to inhibi¬stimulation of insulin release or inhib¬secretion. The inhibitory effect of the the activity of thyroid and adrenal attributed in the hypoglycaemic effect of the
The pineal extract of camel exerted an inhibitory effect 02consumption of different tissue slices of albino rats. esence of glucose in Krebs-Ringer solution was decreased
~e 02consumption lowering effect of the pineal ectract.