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العنوان
Morphopathological Studies on some Lung Affections in Sheep /
المؤلف
Nagy, Abd El-Rahim Amin.
هيئة الاعداد
باحث / عبد الرحيم امين ناجى
مشرف / عبد التواب محمد بهجت
مناقش / حلمى احمد شحاته
مناقش / محمد على محمود السرجانى
الموضوع
Sheep - Diseases.
تاريخ النشر
1976.
عدد الصفحات
200 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
الناشر
تاريخ الإجازة
29/12/1976
مكان الإجازة
جامعة أسيوط - كلية الطب البيطري - Pathology
الفهرس
Only 14 pages are availabe for public view

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from 216

Abstract

Lungs of 980 apparently helbhy beep of both sexes and different ages (ranged from 8 months. to more than 3 years) were examined after slaughtering at Assiut and Cairo abattoirs. 101 lungs are found to be affected with various forms of pneumonia and other pulmonary affections with total incidence of about
10.3%.
In the present work, the criterion used to c1asfy the pulmonary affections was based on the morhohitopatho1cgieai studiea and bacteriological isolates. Such lesions were classified into:
1— Fudetive pneumonia (with medium incidence of 3.9%) which included suppurative pneumonia (2.9%) and
sero—catarrhal or fibrino—necrotiG pneumonia (1%).
2— Interstitial pneumonia with incidence of 1.3% which included focal interstitial pneumonia (gr’u.imo&
0.3%) and, diffuse intersttia1 pneumonia (1%).
3— Pulmonary carcinoma w,th the lowest fncicience of 2%.
4— Pneutnoconiosis with a highest incidence of 4.9%. Bacteriological examination showed that pasteur— ella app. have a more universal localization in all forms of pneumonia. Staphylococci were isolated from actute and chronic suppurative pneumonia. Streptococcus spp. were confined to chronic su.ppurative pnetonia and sero—caterrhal brochopneumonia. Criebaoterium
spp. were identified from chronic suppurative pneumonia. E.coli was isolated from focal interstitial pneumonia as well as pneumononiosis. E.coli with either pasteurella, Staphylococci or streptococci were observed from acute and chronic suppurative pneumonia, But E.ooli with pasteurella were noticed in sero—catarrhal bronchopneuinonia and pneumoconioeis. Anthracoid with pasteurella or E.coli were isolated from pneumoconiosis.
aeteriological1y suppurative pneumonia is classi— fiec1. into:
Chronic siippurat1v pneumonia ue to Coryenbacter— jun app. where the left ‘ung was commonly effected with abscesses of various sizes and ages with cheezy pus surrounded by thick epsule. lVLicroscopically, caseated pus intermixed with calcification appeared Oapsulatéd with a capsule consisted of civrr,i. iycre. . layer of hyalinize4 C.T. then a thin layer ol: new granulation tissue witI lymphoc.ytes later thick healthy layer of C.T. Tha parent.hymel reaction showed focal, to diffuse fibrosis and ruacrophagal reaction.
Chronic suppurative pneumonia due to Staphylococcus
or streptococcus app. in which a consolidated patches wtth abscesses formation were commonly seen.
Microscopioaiiy how4 iffrii ei abscesses
with a liquified pus and the parenchyrna]. reaction showed sero—fjbrjnous reaction,
Chronic suppuratjve pneumonia due to mixed infection by E.coli with pasteu.rella, staphylococcus or Streptococcus spp. were also accompanied by abscesses in a consolidated patches. The abscesses were of different size8 and ages with liquified o± inspissated pus. iILicroscopica11y, revealed. Caseated or liquifje pus of the abscesses with diffuse parenchymal fibrosis and moderate macrophga1 reaction. .Acutê suppurative pnuemonia due to mixed infection by E.colj with pasteurella, staphylococci or streptococci, where consolidated patches were involving the ventral portion of apical, cardianc lobes sometimes anterior portions of diaphragnietic lobes. Mdcroscopica1ly, revealed a picture of acute suppurative bronchopneuonia.
Prom sero—catarrhal or fibrino—necrotic p:’umonj pasteurella spp., streptococcua spp. a’- E.colj with pasteurefla are isolated, where large Donsoljdated patches granular in appearance were seen involved the ventral portion of apical, cardianc and antero—vtr1 portion of diaphragrnatjc lobes.
In interHtltiaj. pneumonia, E.coLi was isolated
from the focal granujoma and non specifjc antrhaoid and E.coli witki. anthracoja. from diffuse forms. The granuloma appear as lentile sized nodule waxy on cutting and usually confined to left diaphragmatjc lobes. Histologically, a proliferating histocytes few giant cells, fibroiblast and esinophilic cells infiltration were seen sometimes with caseated center. Indiffuse interstitial pneumonia the reaction usual]3 exudative (serous) or proliferative with histocytes, small round cells and fibroblastic cells.
In pulmonary carcinoma nc microorganjsn could be isolated. The lesions are confined to right dia phragmatic lobe in a form of a nodule or small patches 0.5 cm. in diameter, withs1ii cut surface. Microscopicall— the neopLastic cells were arranged in single layer forming acini, tubules and solid masses (some o.f aini or tubules contained mucin). The undifferentiated cells were seen orginating from the bronchiolar or bronchial mucous gland which ar infiltrateJ the lung tissues in a forms of nestes or sciid masses.
In pneumoconioajs non specific. micorganisms such as E.coli, anthracoid and mixed infection by anthracoid with pasteurella or E.coli or pasteurella with E.coli were iso’ated. Grossly, all lobes of the lung were unfiorrrily disooulored with black pigments as their bronchial lymph—nodes. Th8 reaction microscopically were diffuse infiltration of pigment in the bronchial, bronchiolar and vessels CDT. also in the alveolar septa. Marked lyinpho—histocytic reaction are observed in the site of pigment infiltration mild chronic proliferating reaction was the prominant features. Histochemically, the black pigmentation in the lung and lymph nodes is proved to be similar to coal if not identical.
Iinuno—morphological studies are done on the broncli— ial lymph nodes by counting plasma cells in both cortex and medulla. Generally, a sharp increase in the total number is recorded in cases of exudative pneumonia (62.5 cells/field and 57.5 cells/field)6 Slight increase in the number was seen in pulmonary carcinoma 21 cells/field. Pneumoconiosis and interstitial pneumonia 42, 30 cells/field respectively occupying a medium position.