الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Proliferative vitreoretinopathy is the most common cause of failure after retinal reattachment. I briefly reviewed the different classifications of PVR, diagnosis of PVR, the pathology and pathogenesis of PVR, different
preoperative, intraoperative risk factors and different drugs reported in
literature used for pharmacological prevention of PVR.
In our study we evaluated the adjunctive 5-FU and LMWH intraoperatively on infusion fluid during vitrectomy procedure to prevent
secondary PVR for cases at high risk.
We operated on 40 patients(20 adjuvant treatment group A and 20 control group B). We had a final attachment rate of 85% in group A and 70
% in group B. which is comparable to results reported in literature.
Adjuvant 5-FU and LMWH during vitrectomy proved safe and effective in cases with higher grades of PVR, hypotony, and traumatic PVR cases. Further studies on a larger scale of patients using one variate for each
study are needed.