الفهرس | يوجد فقط 14 صفحة متاحة للعرض العام |
المستخلص This thesis describes the utility of phthalic anhydride as a key starting material for the preparation of a novel series of phthalazinones and the tricyclic fused phthalazines and antimicrobial activity of some of them. The thesis consists of the following parts: 1) Summary 2) Introduction: In this section brief literatures review of the different methods of preparation and the reactions and applications of phthalazine derivatives. 3) Discussion: It deals with the discussion of the experimental methods adopted for the synthesis of the designed compounds as well as the different analytical methods applied for the characterization of the new compounds. Schemes 1- 6 illustrate the synthetic pathways followed in the Preparation of the target compounds. In this part the author synthesis 2-(3,4-dimethvl-benzoyl)-3,4,5,6-tetrabromo-benzoic acid I by reaction of o-xylene with tetrabromo- phthalic anhydride under Friedl Craft’s conditions. |