الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Asteraceae is the largest family of the plant kingdom with diverse biological actions. Some of the recently reported medicinal importance includes: hepatoprotective, antioxidant, antibacterial, antimalarial and anti-HIV activities. In addition, literature survey revealed that plants of genus Inula has a great reputation as antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, anticytotoxic, antidiabetic, antineoplastic, antihepatotoxic, anaesthetic and cardioprotective agents.
The medical interest has been increased recently in the roots of this genus. Examples are: roots extract of I. helenium showed antioxidant effect, anaesthetic effect and showed a remarkable antineoplastic activity. I. heterolepsis Boiss roots extract had a curative effect on liver, kidney and testis damage in alcoholic rats. I. racemosa roots extract was used traditionally to treat diabetes and has proven effective when tested on experimental animals. It also exhibited significant hepatoprotective properties and was reported to cure myocardial ischemia.
These activities may be attributed to the presence of a wide array of biologically active secondary metabolites including flavonoids, phenolic acids and terpenoids.
Thus, the current study represents a biologically guided fractionation of Inula crithmoides L., family Asteraceae. This work also includes isolation and identification of different components of the biologically active fractions using different physical, chemical and spectral methods. As well as quantitative determination of the major component of the most active fraction by a validated HPTLC method. In addition, antimicrobial screening of petroleum ether extract of fresh flowers of Inula crithmoides L. is performed.
This thesis consists of four parts: