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Abstract present study was performed in Pediatric Department , Banha Faculty of Medicine , Zagagzig University. 50 children (33 males and 17 females ) were chosen from those attending the out-and inpatient clinics of Pediatrics at Banha University Hospital . The selected cases were below 14 years and showed heptomegaly on preliminary examination . All the cases were subjected to complete clinical examination , stool analyss , blood analysis and their sera were isolated for immunological test (I.H.A) and then, the gained data were recorded . The results of this work were presented in figures and tables and the conventional statistical methods were used for their analysis .The results were as follows: _ The mean age of males in the studied cases with hepatomegaly was 5.9 years ( ± 2.6 )whereas the mean age offemales in these cases was 5.5 years (± 3.5) . _ Among all the studied cases with hepatomegaly,3 cases were infected with Fasciola (6%) , all of them (100%) were males having a mean age 7.3 years (± 2.1). _ Fasciola infection was prevalent in the age groups: 4-8 years (33.3%) and over 8 years (66.7%). _ Clinically, all cases (100%) had a triad offever , pallor and tender hepatomegaly with occasional vomiting (33.3%) and jaundice (33.3%). _ Haematologically , infected cases had a mean haemoglobin value 5.8 gmJdl (± 1.3 ) and eosinophilic percent 77% ( ± 1.5 ) . -56- _ Stool examination of the studied cases with hepatomegaly revealed: _No parasites in 19 cases (38%) . _ Only Fasciola in 3 cases (6%) . _ Other parasites in 28 cases (56%) . _ The validity of stool examination techniques in detecting Fasciola eggs, compared to LH.A , was as follows: zero % for floatation (zinc sulphate) techniquc , 33.3% for the 3 successive stool examinations and 100% for formol - ether sedimentation and merthiolate iodi ne formaldehyde concentation techniques. CONCLUSION : 1- Human fascioliasis becomes a new parasitic health problem among Egyptian children. 2- This disease should be suspected in any child having fever, paIlor and tender hepatomegaly, particularly when the blood picture reveals anaemia and marked eosinophilia. |