الفهرس 
Epidemiology of HCCOnly 14 pages are availabe for public view
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Abstract
diiu SurnmaryS ConclusionHepatoeellular carcinoma (HCC) is the third leading cause of death from cancer worldwide. When diagnosed at tin early stage, the treatment of HCC with liver transplantation or surgical resection can be curative. However, despite effective therapies for early stage HCCs and efforts at early diagnosis of HCC through screening of patients at risk for this cancer, most HCCs are diagnosed at an advanced stage. Less than 15% of patients diagnosed vvjlh HCC are eligible for liver Iransplanlaiion or surgical resection with curative intent Early diagnosis of HCC is difficult because:-
fl) HCCs typically are asymptomatic until the tumor is large or infiltrating,
£2) the standard serum screening test, a fetoprotein (AFP), has a poor sensitivity for the detection of small tumors,
(3) the AFP level often is increased in patients with chronic hepatitis C virus infection in the absence of HCC. Easl gudlines 2008 removed it from screening. The Lens culinaris agglutinin-reactive AFP percentage of the total AFP concentration ( [APP-L3/lotal AFP] X 100), or AFP-L3%, has been used as a marker for early diagnosis, for the assessment of therapeutic effects, and for predicting the prognosis of HCC -
This study was performed To evaluate the utility of AFP-L3% in diagnosis of hepatocellular carcinoma (HCC) in Egyptian patients and to study its relationship to tumor characteristics such as size, vascular invasion and metastasis.