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Abstract Polycystic ovary syndrome is a heterogenous disorder of unknown aetiology affecting 5-10% of women of reproductive age. It is a disorder that affects the reproductive, endocrine and metabolic systems and it is the most common cause of anovulatory infertility. It is characterized by chronic anovulation with oligo-amenorrhea, obesity, enlarged cystic ovaries, elevated luteinizing hormone (LH), hyperandrogenism and infertility. Most physician would agree that PCOS can be diagnosed clinically in a woman who has hirsutism, irregular menstrual cycles, obesity and a classic ovarian morphology. PCOS shares some or most components of the metabolic syndrome, manifested by abdominal obesity, insulin resistance, dyslipidemia and atherosclerosis. PCOS patients may represent the largest group of young women at high risk for the possible development of early-onset cardiovascular disease (CVD), diagnosed many years before the clinical onset of the symptoms. |