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Abstract This study included 15 healthy control subjects from the staff of the Hemodialysis Unit (group I) and 64 patients with chronic renal failure under hemodialysis. Of these 25 patients were dialyzed for less than one year (group II) and 39 patients dialyzed for more than one year (group III). Both groups multiblood transfusions. Anti-HCV Abs were highly prevailing among the patients and totally absent from the controls. HCV Abs positive cases represent 72% of group II but all of group III were anti-HCV positive. The results suggested that duration of dialysis augments the effect of all other risk factors beside being a major risk factor by itself regarding HCV infection. Patients with chronic renal failure and on haemodialysis are commonly subjected to the risk of getting viral hepatitis. The common forms of dialysis associated hepatitis include hepatitis A, hepatitis B, hepatitis C, (non-A non-B), cytomegalovirus hepatitis and drug induced hepatitis. The main route HCV transmission is percutaneous transparentral which included haemodialysis, renal transplantation, plasmaphoresis, intervenous drug use and drug addiction. These results of patients groups are highly significant when compared with those of control group. |