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العنوان
Clinicohistopathological and Sonographic Study of the Diabetic Liver and its Correlation with Liver Function Tests /
الناشر
Lamiaa Ali Moustafa EL-Sherief,
المؤلف
EL-Sherief, Lamiaa Ali Moustafa
هيئة الاعداد
باحث / لمياء علي مصطفى الشريف
مشرف / إجلال محمد شوقى حامد
مشرف / نوسة محمود العدوى
مشرف / حسن محى الدين
الموضوع
Diabetes Mellitus Normal Hepatic Morphology and Histology Biopsy and Ultrasound of Liver Liver Function Test The Histopathologic and Morphologic Changes of Diabetic Liver
تاريخ النشر
2000 .
عدد الصفحات
164 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2000
مكان الإجازة
جامعة المنيا - كلية الطب - قسم الامراض الباطنة
الفهرس
Only 14 pages are availabe for public view

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from 187

Abstract

Aim of the work
The aim of the work is to evaluate the histopathologic and sonographic findings of the diabetic liver and its correlation with liver function tests.
Results of this study showed
1- Positive correlation between poorly controlled diabetic patients (high level of fasting, post-prandial blood sugar and glycosylated haemoglobin) and liver enlargement, fatty liver in both IDDM and NIDDM.
2- Hepatomegaly and fatty infiltration were found to be common in IDDM than in NIDDM.
3- No relation between glycaemic control of diabetic patients and total serum bilirubin, total protein and liver enzymes in both IDDM and NIDDM.
4- Positive correlation between glycaemic control of diabetic patients (poorly controlled) and low level of albumin in both IDDM and NIDDM.
5- Positive correlation between duration of diabetes mellitus and liver enlargement, fatty liver in both IDDM and NIDDM.
6- No relation between duration of diabetes mellitus and total serum bilirubin, total protein and liver enzymes in both IDDM and NIDDM.
7- Positive relation between duration of diabetes mellitus and low level of albumin in both IDDM and NIDDM.
The conclusion of histopathologic examination of liver biopsies:
1- Increasing severity of fatty metamorphosis from well controlled diabetes to poorly controlled diabetes was found.
2- Glycogen nuclei and PAS-positive blood vessels in portal tracts were significantly more prevalent in poorly controlled diabetes than in well controlled diabetes.
3- Finally, the distribution of significant liver histopathology in diabetic patient correlates in severity with the degree of impaired glycogen status.