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العنوان
Determinants of Morbidity in Acute Schistosomiasis Mansoni /
الناشر
Atef Farouk EL-Akad,
المؤلف
EL-Akad, Atef Farouk
هيئة الاعداد
باحث / Atef Farouk EL-Akad
مشرف / Anwar Mohammed Orieby
مشرف / Eglal M. Shawky Hamed
مشرف / Ahmed Saad EL-Din Salama
الموضوع
Internal Medicine Schistosomiasis Mansoni Internal Medicine Schistosomiasis Mansoni
تاريخ النشر
1993 .
عدد الصفحات
229 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/1993
مكان الإجازة
جامعة المنيا - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

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Abstract

In summary, the following points with regard to the pathogenices of acute schistosomiasis need to be emphasized:
1- The clinical severity of acute schistosomiasis is closely correlated with the intensity of S. mansoni infection as measured by the concentration of eggs in the stool.
2- Individual cases heavy infections may not be necessary for the classic acute syndrome.
3- The earliest phase of the syndrome can be initiated by parasite antigens present before oviposition.
4- The fact that intensity of infection (egg counts) remains elevated despite the disappearance of symptoms indicates that the host modifies its response to schistosomal antigens.
5- Studies of immune coplex activity and cellular and hormonal immune mechanisms are needed order to clarify the host responses hepatogenesis of acute schistosomiasis.
6- Physicians in suspected new foci should be a ware of the problem and patients with suggesting symptoms of acute schistosomiasis mansoni and if facilities of diagnosis are not available they should be referred to the specialized centers (such as tropical medical department in district and general hospitals) where tools for further investigations are available, and proven infection can be treated.
7- The local health authorities have been aware about the problem. However, awareness of bilharzial incidence or prevalence in any specific area is not enough to evaluate its public health importance, therefore integrated approach through a cross sectional survey aiming at additional information on intensity of infection, prevalence of morbidity with possible socio economic impact and for the possible future of the pattern of the two kinds of bilharzia at any particular geographic area is badly needed.
8- Biologic study of the snail intermediate hosts is an essential part for the control program and for determination of some changes in the transmission dynamics in early infection in any newly discovered foci.