الفهرس | يوجد فقط 14 صفحة متاحة للعرض العام |
المستخلص Clinical rrials in patients with pacemakers for sinus node dysfunction or atrioventricular block (AVB) and implantable cardioverter-defibrillators provide increasing evidence showing that desynchroniztion of ventricular electrical activation and contraction, induced by conventional right ventricular apex(RVA) pacing, is a serious threat for long-term cardiac morbidity and mortality. The risk of heart failure is increased even in hearts with initially normal pump function and in case of part-time ventricular pacing. These epidemiologic data fit with knowledge from decades of pathophysiological research, indicating that right ventricular (RV) pacing creates abnormal contraction, reduced pump function, hypertrophy , and ultrastructural abnormalities . |