الفهرس 
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Abstract
The aim of the present work is:
1- To study the klebsiella rhinoscleromatis bacilli and the frequency with which it occurs in normal individuals and in patients diagnosed clinically as having rhinoscleroma.
2- To demonstrate the effect of experimental intranasal inoculation of klebsiella rhinoscleromatis bacilli in healthy animals.
Conclusions:
This study supports the widely favoured bacterial theory. Klebsiella rhinoscleromatis could be isolated in all cases of the untreated group; however, the poor isolation rate of the organisms in others could be due to the previous treatment taken by the patients. The failure to isolate Klebsiella rhinoscleromatis in the study of 400 apparently healthy individuals supports the contention that it is not a normal commensal; the 5 normal individuals who give positive isolates for Klebsiella rhinoscleromatis could be considered as carriers to the disease.
Using the organism satisfying the currently accepted criteria of Klebsiella rhinoscleromatis isolated from a patient with rhinoscleroma, detectable pathology was produced by intranasal inoculation in rabbits and guinea pigs. The lesion produced was a chronic granulomatous process with many of the features of human scleroma. Attempts to recover the organism from the experimentally induced lung lesions were successful. By these studies we believe Koch’s postulates have tentatively been fulfilled and that Klebsiella rhinoscleromatis bears an aetiological relationship to scleroma. Ultimate proof of the relationship, however, rests in the reproduction of the disease in humans.