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Abstract
Carbimazole is an antithyroid drug used in the treatment of hyperthyrodisim but it was accompanied by many side effects in many mammalian organs.Selenium is an essential animal nutrient has an eviromental, a chemical and an industrial agent in many products. Sodium selenite is commonly used as a directly supplement for the treatment of selenium deficiency. Selenium has along history in chemoprevention of many types of cancer,anti-mutagenic properties, antioxidant and anti-inflammatory effects.