الفهرس | Only 14 pages are availabe for public view |
Abstract Part I Anew one Pot Synthesis of-Aminoquinolines Via Base Promoted Condensation of M-Chloroaniline with B-Arylacylonitrile Derivatives : M-Chloroaniline 1 was allowed to react with B-Arylacylonitrile Derivatives 2a-d .Thus it has been found that 1 reacted with 2a in methanolic sodium ethoxid to yield a compound 7a . Structure 7a the Quinoline Derivative was considered more likely based on analytical and spectral data . moreover , the structure of 7a was confirmed chemically by the reaction of 1 with benzaldehyde to give Schiff base 8, which then reacted with malononitrile to afford 7a . Part II Microwave- Assisted Reactions 2 .One Pot Synthesis of Pyrimido [ 1.2-a] Pyrimidines We Report here a simple route for synthesis of Pyrimido [1.2-a] – Pyrimidine Derivatives under microwave irradiation. Thus it has been found that when an equimolor mixture of 2-aminopyrimidine 1. benzaldehyde 2a and malononitrile 3a in the presence of piperidine as a catalyst was irradiated in a micro oven for 3 minutes at 650 watts , a compound 6a is formed . Part III Microwave – Assisted Reactions 3. One Pot Synthesis of Pyrimido [1.2-a] -6.7.8.9-Tetrahydroquinazolines and Pyrimido [1.2-a]-2.3-Dihydro -5-Azaindenes |