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العنوان
Spectrophotometric Determination Of Some Pyrazolone And Pyrazolidine Derivatives In Their Pharmaceutical Preparations =
الناشر
Mohamed El Sayed Abd El-Hamid,
المؤلف
Abd El-hamid, Mohamed El Sayed.
هيئة الاعداد
مشرف / حامد عابدين توفيق
مشرف / محمود عبد الهادى السيد
باحث / محمد السيد عبد الحميد
مشرف / محمود عبد الهادى
الموضوع
Pharmaceutical Analytical Chemistry.
تاريخ النشر
1977 .
عدد الصفحات
157 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1977
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Analytical Chemistry.
الفهرس
Only 14 pages are availabe for public view

from 190

from 190

Abstract

Amidopyrine, aritipyrine and dipirone are the pyrazolone derivatives of pharmaceutical interest. Those f pyrazoli— dine derivatives are phenylbutazone, oxyphenbutazone arid sulphinpyrazon-e.
A general introduction and a short survey for the methods of assay was given iiip artI. The majority of the nethods sotfar reported in the literature are titrimetric, colorimetric or spectrophotometric.
The experimental in the present thesis is presented in i’t II;the unit—dose assay of the previous mentioned conTpounds in their pharmaceutical formulation;and part IIIacay of certain two—component mixturee.
2art fl includes the items mentioned in the fo)lowin paragra— phes.
The chargetransfer complex formed by the interaction between electron acceptor (dichlorobenzoauinone, DCBQ)and elec— trori donor (amiodpyrirre or antipyrine) was used for the assay of these drugs in tablets. The conditions suitable for the formation of complex wsre worked out. The determination of
+
no1ecular ratio of reactants and association constit were
also described. Application of molar—ratio method indicates that 1:3. and 1:2 donor-acceptor complexes are formed in
;1]