الفهرس 
chabter 1 : introductionOnly 14 pages are availabe for public view
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Abstract
a) Although proteinuria together with heamaturia are the cardinal signs of Schistosoma infection yet proteinuria was very little investigated. One report by German Workers investigation proteinuria in Sudanese patients and provisionally showed some increase in 3 proteins which they suggested albumin, transferrin and IgG. However few other protein bands were recorded by them but without any comment.
In the present investigation proteinuria in Egyptian Sch:stcsoma patient was investigated in some detajl.
Evaluation of different protein precipitating agent was carried out and among those investigated are ethanol, acetone, ferric chloride, tricholoro acetic acid and phosphotungistic acid. Phosphotungistic acid gave the maximum number of bands and the highest relative concentration. Accordingly, it was chosen as the precipitating agents for urine proteins in all, further investigation.
Urine proteins from different normal age groups, up to 15; 15-25 and above 25 years old when subjected for DISC-PAGE electrophoresis gave nearly the same number of protein bands and there was no significant variation in relative concentration of different bands in the three age groups. It can be concluded that in normal persons with different age groups and using DISC-PAGE. The number of protein bands and their relative concentration coincided fairly well as shown in the text.
Proteins obtained from patients and using DISC-PAGE, in the first patient age group up 15 years there was significant difference in the relative concentration of all proteins when compared with corresponding normal age group. In addition other new protein bands number 12, 14, 15, 16, 17, and 18 were recognized and together their relative concentration accounted for 8.38% of the total protein.
In the next patients age group 15-25 years of age there was also significant increase in the relative concentration of urine prutein when compared with the same normal age group and in addition new protein bands number 13, 14, 15, 16, 17, 18, and 19 could be detected and accounted for 9.34% from total protein.
In the third patient age group above 25 years old similar results were obtained. Significant increase in corresponding protein bands when compared with same normal age group in addition to new protein bands number 12, 13, 14, 15, 16, and 17 which accounted for 13.23% of total protein. When we compare the three patient age group with their corresponding to normal age group we observed significant increase in all protein bands.
we can see that there is increase in both proteins of low and high molecular weight. Suggesting that in schistosomiasis patients proteinuria is due to both tubular and glomerular dysfunction.