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Abstract
This study was designed to quantify the risk of cerebrovascular stroke among people with migraine (with and without aura), also to find out the characteristics of stroke (regarding clinical presentation. radiological finding, comorbid risk factors, specially oral contraceptives, and outcome) in migrainous in comparison to non migrainous patients. This study was carried out on forty patients suffering from cerebrovascular stroke. They were compared to another forty control subjects without history of stroke. Each patient in this study was subjected to thorough medical and neurological history taking including their history of vascular risk factors, interview about their history of headache using headache sheet. Complete general and neurological examinations, laboratory work up for risk factors, ECG, Echo-cardiography, carotid duplex, CT scan were done. The severity of stroke assessed by using outcome scales, NIHSS and Barthel Index (at time of entry and every two weeks for two months) The results of this study showed that: There was no significant difference between stroke and control group and between migrainous and non-migrainous control patients regadring demographic factors, clinical and laboratory risk factors. But within the stroke group, hypercholesterolemia show significant difference and Contraceptive pills administration show highly significant difference in
migrainous in comparison to non-migrainous patients. There is a statistically significant difference between stroke patients and control subjects regarding history of migraine but there is no statistically significant difference regarding type of migraine. There is no statistically significant difference between migrainous stroke and control patients regarding frequency and duration of migraine and use of triptan, but they are higher in stroke than control migrainous patients. There is statistically significant difference between migrainous and non-migrainous stroke patients as regard family history of migraine. There is no significant difference between migrainous and nonmigrainous stroke patients as regard clinical presentation of stroke except for hemiplegia which show highly significant difference in non-migrainous in comparison to migrainous patients. There is no statistically significant difference between migrainous and non-migrainous stroke patients regarding distribution of C.T results except for thalamic lesions which show highly significant difference in non-migrainous in comparison to migrainous patients, but regarding site of lesion there is predominance of PCA affection (50.0%) in migrainous patients in comparison to non-migrainous patients where MCA affection predominate (83.4.5%).