Search In this Thesis
   Search In this Thesis  
العنوان
Clinicohistopathological and Sonographic Study of the Diabetic Liver and its Correlation with Liver Function Tests
الناشر
Lamiaa Ali Moustafa EL-Sherief ,
المؤلف
EL-Sherief, Lamiaa Ali Moustafa
هيئة الاعداد
باحث / Lamiaa Ali Moustafa EL-Sherief
مشرف / Iglal Mohamed Shawky
مشرف / Nousa Mahmoud EL-Adawy
مشرف / Hassan Mohey EL-Dein
الموضوع
Diabetes Mellitus Normal Hepatic Morphology and Histology Biopsy and Ultrasound of Liver The Histopathologic and Morphologic Changes of Diabetic Liver Liver Function Test
تاريخ النشر
2000 .
عدد الصفحات
164 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2000
مكان الإجازة
جامعة المنيا - كلية الطب - أمراض الباطنة
الفهرس
Only 14 pages are availabe for public view

from 189

from 189

Abstract

Aim of the work
The aim of the work is to evaluate the histopathologic and sonographic findings of the diabetic liver and its correlation with liver function tests.
Results of this study showed
1- Positive correlation between poorly controlled diabetic patients (high level of fasting, post-prandial blood sugar and glycosylated haemoglobin) and liver enlargement, fatty liver in both IDDM and NIDDM.
2- Hepatomegaly and fatty infiltration were found to be common in IDDM than in NIDDM.
3- No relation between glycaemic control of diabetic patients and total serum bilirubin, total protein and liver enzymes in both IDDM and NIDDM.
4- Positive correlation between glycaemic control of diabetic patients (poorly controlled) and low level of albumin in both IDDM and NIDDM.
5- Positive correlation between duration of diabetes mellitus and liver enlargement, fatty liver in both IDDM and NIDDM.
6- No relation between duration of diabetes mellitus and total serum bilirubin, total protein and liver enzymes in both IDDM and NIDDM.
7- Positive relation between duration of diabetes mellitus and low level of albumin in both IDDM and NIDDM.
The conclusion of histopathologic examination of liver biopsies:
1- Increasing severity of fatty metamorphosis from well controlled diabetes to poorly controlled diabetes was found.
2- Glycogen nuclei and PAS-positive blood vessels in portal tracts were significantly more prevalent in poorly controlled diabetes than in well controlled diabetes.
3- Finally, the distribution of significant liver histopathology in diabetic patient correlates in severity with the degree of impaired glycogen status.