الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
Aim of the work
To examine the effect of addition of antioxidant therapy and naloxone to the classical treatment of head injury on the outcome of the patient.
Summary
The study included 90 patients with moderate head trauma (GCS score= 8-12) without other significant injuries.
After initial resuscitation to correct hypoxia and hypotension if present, routine intensive care managements were done for every patient. At the same time, blood samples were taken on admission then on third and seven days for measurement of serum triglycerides, cholesterol, C - reactive protein, vitamin A, vitamin E. blood samples were taken routinely at regular intervals for analysis of blood gases.
The results of the current study revealed that there is significant improvement in the outcome of patients with moderate head trauma after addition of antioxidants and naloxone as measured by Glascow Coma Score.
In this study, it was found that serum concentrations of triglycerides and cholesterol and C-reactive protein were significantly lower than the control values after the addition of antioxidants to the ordinary lines of treatment, and show more decrease after addition of naloxone to treatment.
The results of the present study demonstrated a significant increase in serum levels of vitamin A and vitamin E in comparison to control values after addition to either antioxidants alone or the addition of antioxidants and naloxone to the treatment of patients with moderate head trauma.