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Abstract
Natural Pharmaceuticals have been gaining worldwide acceptance as a prime source of medicinal cures. Regardless of the form of natural preparation, some degree of quality control should exist. Quality, safety, and efficacy are the general requirements for new drugs worldwide. Inadequate quality control allows adulterated and often toxic products to reach the market, which directly jeopardize public safety. Ten phytopharmaceuticals were selected from the Egyptian market containing Ginkgo biloba extracts (4 products), Silybum marianum extracts (3 products), and Echinacea species extract (3 products). These phytopharmaceuticals were analyzed for the determination of the active constituents using reversed phase high performance liquid chromatoghraphy. In this work four, simple, sensitive, and accurate methods for the standardization of these phytopharmaceuticals were developed. As far as efficacy is concerned, safety should be the overriding criterion to be proved for the herbs that are used as drugs. Owing to the very low concentrations, analyses of heavy metals were carried out by using atomic absorption spectrophotometric method. A published Gas Chromatographic (GC) method was used for the analysis of pesticide residues and High Pressure Liquid Chromatographic (HPLC) method