الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
1. Hepatitis B virus is still considered to be an important public health problem in Egypt.
2. Our study revealed a prevalence of 1.98% of chronic HBV infection among blood donors in the Blood Transfusion Services Center in Minia Governorate. We included only 62 donors with the highest O.D. for HBsAg for detection of 50 DNA positive donors for subsequent genotyping.
3. Using the Restriction Fragment Length Polymorphism technique for genotyping, 50 blood donors proved to be genotype D, which is the most prevalent genotype in Egypt as stated by both Egyptian an international studies.
4. Our study revealed that 82% of infected donors were males and 18% were females (male predominance).
5. ALT levels were normal in 45 samples and slightly elevated in only 5 samples (10%) with a weak correlation between genotype D and ALT level.
6. HBeAg negative samples constituted 84% of our 50 DNA positive donors, while HBeAg positive samples constituted 16% which mean that HBeAg negative is the most prevalent serological type in Egypt as stated by many authors.
7. The prevalence of Genotype D matches the prevalence of precore mutants in Egypt.