الفهرس 
Subjects and methodsOnly 14 pages are availabe for public view
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Abstract
This study wascarried out on 83 subjects, 53 patients with AIH type I, II, PSC, PBC and chronic viral hepatitis, 33 of them were females and 20 were males, selected from inpatients of the internal medicine department, benha university hospital and liver institute, Shebein Alkom university hospital and internal medicine department, Cairo university hospital and GIT center, Mansoura university hospital, and 30 healthy volunteers serving as control group. The patients were classified into 4 groups; Group I; patients with auto –immune hepatitis : it comprised 28 patients, 17 of them with AIH type I, and 14 with AIH type II. Group II; patients with primary sclerosing cholangitis; it comprised 12 patients, 6 of them were primary sclerosing cholangitis with ulccrative colitis. Group III; it included 8 patients with primary biliary chirrosis. Group IV; it comprised 5 patients with chronic viral hepatitis, 3 of them were due to HCV and 2 were due to HBV. The aim of this work was to study the prevalence of ANCA in patients with autoimmune liver disease and to shed light on the relation between these antibodies and the cause, severity, clinical presentation and activity of autoimmune liver disease and verification of specificity and sensitivity of these antibodies in diagnosis of autoimmune liver disease.