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Abstract The aim of this study was to evaluate the diagnostic accuracy of TVUS, SIS and office hysteroscopy in cases with abnormal perimenopausal bleeding. We compared the findings of TVUS, SIS and office hysteroscopy with the final diagnosis established by hysteroscopic guided endometrial biopsy. We conclude that the great diagnostic advantages of the endoscopic technique and the extremely high acceptance and tolerability by the patients may widen the use of the procedure. The prudent selection of appropriate tests depends upon their ability to characterize the anatomic lesions most highly suspected after thorough initial evaluation. Other variables that the clinician must balance include patients preference, available expertise, local costs and availability, risks, and discomfort. Ultimately, test selection should be guided by the underlying principle that the results are capable of changing the clinical management of a patient in a meaningful way. |