الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of this work is to evaluate the role of transvaginal sonographic study of the endometrium and Doppler velocimetric measurement of the uterine artery as screening non-invasive procedures to detect endometrial pathology in case of pre, and post menopausal bleeding and to correlate the sonographic results with histopathological finding in order to discriminate normal from pathological endometrium. Conclusion: This study showed that patients with abnormal endometrial pathology had a mean endometrial thickness that was significantly higher than other patients with normal endometrium. And similarly, the Doppler indices showed levels that were significantly lower in patients with abnormal endometrial pathology. This study suggests a cut off limit of 6 mm for the diagnosis of normal endometrium in pre menopausal patients, and 4mm in post menopausal patients. These cut off limits were associated with a sensitivity of 60% and 88, 9% respectively, while the specificity was 64% and 74,5% respectively. According this study suggests that endometrial thickness measurement is more valuable and accurate in patients with post menopausal than in patients with pre menopausal bleeding. Doppler velocimetric study of the uterine artery offers another simple non invasive valuable method in screening cases of pre and post menopausal bleeding and the present study recommend the use of 0.83 and 3.83 as a cut off values for uterine artery RI and PI respectively to discriminating normal endometrium from abnormal pathological endometrium. These values had resulted in a sensitivity of 87% and a specificity of 73.8% for RI, a sensitivity of 84% and specificity of 87% for PI, giving this technique a great reliability in differentiating normal for pathological patterns in cases of pre and post menopausal bleeding. |