الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of the study is to give a preliminary idea about the prevalence of β-thalassaemia carries in Beni-Suef, and construction of programs for prevention of β-thalassaemia in after coming generations in this governorate based on carrier screening. Conclusion: From this study, it could be concluded that the carrier rate of β-thalassaemia is not less than 7.4% with the following: - ) 6.1% pure β-thalassaemia or typical β-thalassaemia with a gene frequency of 0.0305. - ) 1.1% of β-thalassaemia with a gene frequency of 0.005. - ) 0.2% combination of thalassaemia and other variants with a gene frequency of 0.001. - ) One case of HPFH. The carrier rate of α-thalassaemia is not more than 4.6% with a gene frequency of 0.023 and one case of Hb H disease. - ) Still there is 0.5% who showed border line Hb A2 level in need of further investigation. - ) A rate of 14% prevalence of iron deficiency is detected which is expected. - ) These results revealed that, β-thalassaemia is a major health problem in Beni-Suef that needs all efforts to put a solution for protection of the after coming generations. |