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الملخص العربى
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Introduction
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Anatomical and Physiological Considerations
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Anatomy of the airway
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Physiology of Respirutory System
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Normall Spontaneous Breathing
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Mechanics of respiration
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Inspiration
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Expiration
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gas Flow and Pressure Grdients during Ventilation
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Pulmonary Mechanics
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Compliance of the lungs and chest wall
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Resistance to gas flow
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Time Constant
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Work of breathing
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Components of work of Breathing ··W. O. B:’
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Lung volume and capacities
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Ventilation Perfusion Ratio
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Ventilation
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Distribution of ventilation
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Pulmonary perfusion
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Distribution of perfusion
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Ventilation-perfusion relationships
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Dead Space
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Shunts
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Oxygen transport
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Passive respiratory mechanics
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Carbon Dioxide Transport
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Bohar and Halden effect
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history of venttlator therapy
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Objectives of Mechanical Ventilation
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Physiologic Objectives
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Clinical Objectives
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Types of mechanical ventilation
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Invasive ventilation
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Tracheal Intubation
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The intubation procedure
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Precaution
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Axes of intubation
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Modalities of invasive ventilation
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Negative pressure ventilation
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Positive pressure ventilation
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Negative pressure ventilation
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CNEP might also produce the following complications
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Volume ventilation
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Pressure-limited time cycled ventilation
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Noninvasive ventilation
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History of noninvasive ventilation
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MODALITIES OF NONINVASIVE VENTILATION
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Negative pressure ventilation
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Noninvasive positive-pressure ventilation
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Mechanisms of action
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Inhalation and exhalation
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BIPAP ventilator versus conventional ventilator
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Nasal mask versus face mask
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Patient selection
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Guidelines for the use of NPPV in patients with acute respiratory failure
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Protocol for Initiation of NPPV in patients with acute respiratory failure
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Indications of Mechanical Ventilation
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Acute Respiratory Failure
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Pulmonary oedema and respiratory failure
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Acute Respirator)’ Distress Syndrome (ARDS) in Children
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•• La rvngcotracheobronchiris” Croup
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Epiglotitis
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Cvstic Fibrosis
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Bronchiolitis
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Mechanical Ventilation in the Absence of Respiratory failure
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Asthma
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Closed Head Injury
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Increased Work of breathing
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Disorders resulting in increased work of breathing
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Low Respiratory rate
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Sever Shock
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Ventilatory Modes
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Specific Modes of Ventilation
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Standard Modes
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Assist-Control (A/C)
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Synchronized Intermittent Mandatory Ventilation
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Pressure Support Ventilation (PSV)
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Continuous Positive Airway Pressure (CPAP)
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.\lternnte Modes of Ventilation
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High-Frequency Ventilation(HFV)
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Inverse Ratio Ventilation (IRV)
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Airway Pressure Release Ventilation (APRV)
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Weaning from mechanical ventilation
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Defenition
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Benefits of reducing ventilation times include
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Factors to consider in Weaning from the ventilator
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On-ventilator derived parameters
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Weaning parameters
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Indications for weaning
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Measure weaning parameters
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Extubation
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Protocol for extubation
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Major causes of extubation failure
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Weaning protocol
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Weaning technique
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Modes of Weaning
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Spontaneous Breathing Trials (SilTs)
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Synchroruzed intermittent Mandatory ventilation Mode(SlMV)
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Pressure Support Ventilation Weaning
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New Weaning Modes
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CPAP as a method of weaning
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Failure to wean
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Recognition of Weaning Failure
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Factors contributing to weaning failure
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Ventilator induced lung injuries in pediatrics
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Pathogenesis of Ventilator induced lung injuries
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Pathophysiology of ventilator induced lung injuries
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Manifestation of VlLI
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Mechanisms ofVILI
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Alveolar repair and fibrosis following lung injury
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Complications of Mechanical Ventilation
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Complications due to assisted ventilation and endotrachcnl intubation
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Bronchopulmonary Dysplasia (BPD)
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Air leak (extraneous air syndrome)
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Pulmonary interstitial emphysema (PIE)
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Pneumothorax
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Pneumomediastinum
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Pneumopericardium
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Pneumoperitoneum
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Volutrauma and Barotrauma
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Retinopathy ofprematurity (ROP)
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Major determinants of VILI
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Ventilator determinants of VILI
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lnspired oxygen fraction
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Carbon dioxide
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Patient determinants of VILI
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Biologic Markers ofInflammation in Clinical Studies
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Adjunctive Therapies to Lung-Protective Ventilation
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Adj uncts to traditional mechanical ventilation in pediatrics Surfactant therapy
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Avoidance ofventilator induced lung injuries
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Prevention of ventilator-induced lung injury
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Summary
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References