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Abstract
This study was designed to investigate the changes that will occur in leptin in alloxan-induced diabetic rat and the effects of this changes on insulin , blood glucose and lipid metabolism,
A total of 80 Male Sprague-Dawley rat, from them 40 mature 150 + 10 g b.w.and the other 40 rats are immature 80 ± 10 g B. W. were used in this study, this rats ware accommodated at the animals house in faculty of vet. Med. Zagazig university for 15 days before the experiment, and were kept on standard diet