الفهرس 
REVIEW OF LITETERATURE
HepatitisOnly 14 pages are availabe for public view
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Abstract
This work aimed to study the post renal transplant hepatic dysfunction regarding incidence, causes, effect of different immunosuppressive drugs as well as its outcome in the renal transplant patients. The results showed that kidney transplant recipients are susceptible to various degrees of post transplant hepatic dysfunction and that recipients with HBs-antigenemia are at high risk without serious hepatic derangement. HBs antigenemia per se is not a contraindication for kidney transplantation. Special care should be directed for patients who were HBsAg positive prior to transplantation in a trial to decrease the expected higher incidence of post transplant hepatic dysfunction. Also, screening of blood and kidney donors for HBsAg, CMV and, if possible for markers of NANB virus(es), are essential for decreasing the incidence of post transplant hepatic dysfunction. Immunosuppressive drugs related hepatotoxicity was among the most important causes of post transplant hepatic dysfunction. Periodic monitoring of liver functions and cyclosporin blood level (with adjustment of the dose) decrease the incidence of immuno-suppressive drugs related hepatotoxicity.