الفهرس 
titleOnly 14 pages are availabe for public view
 |  | from | 324 |  |  |
| | | from | 324 | | |
Abstract
DCs constitute a distinct lineage of white blood cells development with some unique features, such as their origin from myeloid and lymphoid progenitors. Two pathways of DC differentiation have been described: thymic DC from a hematopoietic progenitor with lymphoid potential, and DC related to Langerhans cells generated from myeloid precursors using GM-CSF. In addition, both myeloid and lymphoid-restricted precursors can generate CD8α- and CD8α+ thymic DCs, and that CD8α- DC can generate CD8α+ splenic DCs