الفهرس | Only 14 pages are availabe for public view |
Abstract Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long term damage, dysfunction and failure of various organs, especially the eyes, kidneys, nerves, heart and blood vessels.Type 2 DM is the predominant form of diabetes world wide accounting for about 90 - 95% of cases and its prevalence is expected to rise more rapidly in the future because of increasing obesity and reduced activity levels.The prevalence of macrovascular disease is markedly increased among individuals with diabetes mellitus. Its major clinical manifestations are consequences of atherosclerosis of coronary arteries, cerebral arteries, and large arteries of the lower extremities . |