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Abstract
Growth hormone is a polypeptide hormone secreted by the anterior
pituitary gland. Both GH excess and deficiency may cause increased risk for
cardiovascular morbidity and mortality.
The aim of our study was to evaluate the effects of GH deficiency and
GH replacement therapy on left ventricular mass and function by
echocardiography as well as lipid profile during childhood. Sixty patients
documented to have GHD were included in the present study.
Color doppler echo cardiography was performed for assessment of left
ventricular systolic and diastolic functions, calculation of myocardial
performance index, left ventricular mass and left ventricular mass index.
Key Words: Growth hormone deficiency - Growth hormone therapy-
Left ventricular mass - Left ventricular systolic and
diastolic functions